Integrative Strategies for Managing Endometriosis—A Comprehensive Narrative Review

Abstract

Endometriosis is a chronic, estrogen-dependent inflammatory disorder affecting 10–15% of women of reproductive age. It contributes to chronic pelvic pain, infertility, and diminished quality of life. While conventional therapies—including hormonal agents, NSAIDs, and surgery—can offer symptom relief, recurrence remains high, prompting many patients to explore integrative and naturopathic approaches.

This narrative review synthesizes findings from 27 clinical studies—including randomized controlled trials, systematic reviews, and meta-analyses—evaluating dietary, nutraceutical, botanical, acupuncture, and lifestyle interventions for endometriosis management.

Anti-inflammatory dietary patterns such as the Mediterranean and low-FODMAP diets were associated with reduced pain and inflammation. Nutraceuticals, including omega-3 fatty acids, curcumin, resveratrol, and vitamins C, D, and E, showed potential to alleviate pelvic pain and oxidative stress. Acupuncture and Chinese herbal medicine demonstrated benefits in symptom reduction and quality of life. Mind–body therapies such as yoga and multimodal self-management programs improved psychological well-being and coping.

Collectively, these modalities offer low-risk, mechanism-based adjuncts that can be integrated into patient-centred care while large phenotype-stratified trials are conducted.